December 1, 1977Diabetes
Postprandial Plasma-glucose and -insulin Responses to Different Complex Carbohydrates
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Implication
Experimental study reveals divergent postprandial glucose and insulin responses to complex carbohydrates in humans, indicating that food source impacts glycemic control.
Key Points
- To compare postprandial plasma glucose and insulin responses elicited by different complex carbohydrate sources against pure dextrose.
- Administered carbohydrate meals containing an equivalent of 50 gm of glucose from dextrose, rice, potato, corn, or bread in 16 subjects.
- Measured postprandial plasma glucose and insulin levels, stratifying subjects based on their one-hour post-dextrose plasma glucose response.
- Dextrose and potato elicited similar, marked plasma glucose and insulin elevations, whereas rice and corn produced significantly lower responses, with bread yielding an intermediate insulin response.
- Subjects with the highest one-hour glucose response to dextrose exhibited substantially magnified differences in plasma glucose and insulin curves across carbohydrate types compared to low responders.
Cite This Study
Crapo et al. (1977) studied this question.