Why the study?
A better understanding of the correlation between monocyte subsets and inflammatory signaling in patients with atherosclerotic disease in ACS is essential for developing more effective cardiovascular therapies.
Does acute coronary syndrome (STEMI/NSTEMI) increase monocyte activation and mobilization compared to patients without obstructive coronary lesions?
Does acute coronary syndrome (STEMI/NSTEMI) increase monocyte activation and mobilization compared to patients without obstructive coronary lesions?
Acute myocardial infarction, particularly STEMI, is associated with a significant early increase in classical monocyte mobilization compared to patients without obstructive coronary disease.
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Monocyte subset correlations in ACS remain hypothesis-generating; prospective studies needed before clinical adoption.
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Guimarães et al. (2023) studied this question.
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