Why the study?
Does common femoral artery intima-media thickness correlate with the severity of coronary artery disease in symptomatic patients undergoing angiography?
Does common femoral artery intima-media thickness correlate with the severity of coronary artery disease in symptomatic patients undergoing angiography?
Femoral intima-media thickness correlates strongly with the presence and angiographic severity of coronary artery disease, suggesting it could serve as a novel cardiovascular risk marker.
Femoral IMT may aid noninvasive CAD assessment in symptomatic patients; leaves open its incremental prognostic value in prospective studies.
The carotid artery intima-media thickness (IMT) is an established surrogate marker of vascular risk. We assessed the common femoral artery IMT and its correlation with coronary artery disease (CAD). We also assessed the influence of vascular risk factors on the femoral IMT. Patients (n = 180; mean age 60.4 ± 10.5 years) who had undergone coronary angiography due to symptoms of CAD were enrolled in this study. We found significantly higher values of femoral IMT in patients with CAD than in those without CAD (P = .0000). A strong positive correlation between femoral IMT and the severity of CAD expressed by the Gensini Score (P = .0000) was observed. There was a positive correlation between femoral IMT and levels of triglycerides (P = .017), body mass index (BMI; P = .036), male gender (P = .0000), and smoking (P = .028). There was a negative correlation between femoral IMT and the level of high-density lipoprotein-cholesterol (P = .001). Femoral IMT could be a novel cardiovascular risk marker.
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Kirhmajer et al. (2010) studied this question.
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