Why the study?
Does the combination of ischemic preconditioning and angiotensin II-induced preconditioning improve postischemic recovery and mitochondrial function in Langendorff-perfused rat hearts compared to either alone or control?
Does the combination of ischemic preconditioning and angiotensin II-induced preconditioning improve postischemic recovery and mitochondrial function in Langendorff-perfused rat hearts compared to either alone or control?
The combination of ischemic preconditioning and angiotensin II-induced preconditioning synergistically improves mitochondrial respiration and additively enhances ventricular postischemic recovery in rat hearts.
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Hypothesis-generating for IPC/APC synergy in rat hearts; clinical translation requires prospective human trials.
Nuñez et al. (2014) studied this question.
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