Population
Single cells from bull-frog atrium (bull-frog atrial myocytes)
Comparison
Voltage clamp measurements and computer… vs Various ionic solutions
Design
Preclinical
Authors
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Supports NCX tail currents near rest in frog atria; leaves open mammalian relevance and clinical arrhythmia implications.
In bull-frog atrial myocytes, the Na+-Ca2+ exchanger generates a slow inward tail current that may be significant near the resting potential and is modulated by intracellular Ca2+-binding proteins.
Campbell et al. (1988) studied this question.
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