Why the study?
Does central obesity compared to peripheral obesity worsen sympathetic and metabolic function in normotensive subjects?
Population
82 age-matched normotensive subjects, comprising 36 lean subjects, 20 with peripheral obesity, and 26 with…
Comparison
Central obesity (CO) vs Peripheral obesity (PO) and lean subjects
Design
Cross-sectional
Authors
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Central obesity may signal elevated sympathetic and metabolic risk in normotensives; leaves open causal role in hypertension development.
Does central obesity compared to peripheral obesity worsen sympathetic and metabolic function in normotensive subjects?
Central obesity is associated with greater sympathetic activation and insulin resistance compared to peripheral obesity in normotensive individuals, independent of baroreflex mechanisms.
Grassı et al. (2004) studied this question.
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