Why the study?
Does diabetes induced by streptozotocin alter the mechanical properties of the arterial system in male and female rats?
Does diabetes induced by streptozotocin alter the mechanical properties of the arterial system in male and female rats?
Diabetes decreases aortic distensibility and impairs wave reflection in both male and female rats, while only male diabetic rats show detrimental changes in resistance arterioles.
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Should not inform clinical practice; leaves open translation of rat arterial changes to human diabetes outcomes.
Chang et al. (2003) studied this question.
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