Population
Elderly and hypertensive subjects
Design
Review
Authors
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May support vasodilator preference in elderly isolated systolic hypertension; leaves open prospective trials targeting wave reflection.
Understanding arterial pressure waveforms and wave reflection provides mechanistic insights into isolated systolic hypertension, ventricular-vascular interaction, and the therapeutic benefits of vasodilator drugs.
Michael F. O’Rourke (1994) studied this question.
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