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June 12, 2020Paediatrica IndonesianaOpen Access

Pre- and post-operative serum albumin levels ≤ 3.00 g/dL were associated with higher risk of post-operative sepsis (RR 3.4; 95% CI 1.54 to 7.51) and relaparotomy (RR 3.84; 95% CI 1.28 to 1.49).

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Why the study?

Patients undergoing abdominal surgery with hypoalbuminemia face increased risk of postoperative complications, but the prognostic role of albumin levels in children remained unclear.

Does hypoalbuminemia (serum albumin ≤ 3.00 g/dL) increase the risk of post-operative complications in children undergoing abdominal surgery?

Population

201 children aged 29 days to 18 years undergoing abdominal surgery admitted to the PICU

Comparison

Pre- and post-operative serum albumin levels ≤ 3.00 g/dL vs higher levels

Design

Retrospective cohort study

Authors

RDRismala DewiFSFreddy Guntur Mangapul SilitongaIMIrawan Mangunatmadja

Discussion

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Overview

Hypoalbuminemia signals higher sepsis and relaparotomy risk after pediatric abdominal surgery; leaves open whether correction alters outcomes.

Structured PICO

Does hypoalbuminemia (serum albumin ≤ 3.00 g/dL) increase the risk of post-operative complications in children undergoing abdominal surgery?

P
Population
201 children aged 29 days to 18 years who underwent abdominal surgery, had serum albumin levels measured pre-operatively and within 48 hours post-operatively, and were hospitalized in the Paediatric Intensive Care Unit of Dr. Cipto Mangunkusumo Hospital, Indonesia.
I
Intervention
Pre- and post-operative serum albumin levels ≤ 3.00 g/dL (hypoalbuminemia)
C
Comparator
Serum albumin levels > 3.00 g/dL
O
Outcome
Post-operative complications (sepsis, surgical site infection, shock), length of stay in PICU, dehiscence, relaparotomy, and postoperative mortalityhard clinical

Hypoalbuminemia in children undergoing abdominal surgery is associated with an increased risk of post-operative sepsis, relaparotomy, and longer PICU stay.

Cite This Study

Dewi et al. (2020) studied this question.

synapsesocial.com/papers/6a70c948a528af2d65c3bc90https://doi.org/10.14238/pi60.3.2020.149-53
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Impact of albumin levels on clinical outcomes in children underwent abdominal surgery2020 · 1 citations
  2. 2Preoperative hypoalbuminemia and severe acute malnutrition as prognostic factors for postoperative complications in major abdominal surgery: A single-center retrospective study2023 · 1 citations
  3. 3Evaluation of pre-operative albumin in the prediction of outcomes of emergency laparotomy2022
  4. 4Factors affecting perioperative serum albumin variation and short term complications in pediatric patients undergoing major gastroenterology surgery2020
  5. 5Peri-Operative Fall in Serum Albumin Levels Correlate Well With Outcomes in Children Undergoing Emergency Abdominal Surgery: A Prospective Study From a Resource-Limited Setting2022 · 5 citations