What question did this study set out to answer?

To review the prevalence, clinical spectrum, and underlying pathophysiological mechanisms of cardiovascular involvement in patients with dermatomyositis and polymyositis.

September 16, 2006Lara D. VeekenOpen Access

The heart in dermatomyositis and polymyositis

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Authors

ILIngrid E. LundbergUniversity of Geneva

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Implication

Clinical review reveals frequent subclinical cardiac abnormalities in dermatomyositis and polymyositis, indicating heart disease as a leading cause of mortality.

Key Points

To review the prevalence, clinical spectrum, and underlying pathophysiological mechanisms of cardiovascular involvement in patients with dermatomyositis and polymyositis.
Narrative synthesis of clinical studies evaluating cardiac manifestations and diagnostic findings in polymyositis and dermatomyositis.
Assessment of electrocardiographic abnormalities, overt cardiac events, and vascular or myocardial tissue pathology.
Clinically apparent cardiac involvement is relatively rare, yet cardiovascular manifestations remain a major cause of mortality in myositis.
Subclinical cardiac manifestations occur frequently and consist primarily of conduction abnormalities and arrhythmias identified on electrocardiogram.
Overt clinical disease presents most often as congestive heart failure, severe conduction defects leading to complete heart block, and coronary artery disease secondary to myocarditis and small-vessel pathology.

Cite This Study

Ingrid E. Lundberg (2006) studied this question.

synapsesocial.com/papers/6a70ca52a2d7cf2e39c2b75a https://doi.org/10.1093/rheumatology/kel311

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Implication

Clinical review reveals frequent subclinical cardiac abnormalities in dermatomyositis and polymyositis, indicating heart disease as a leading cause of mortality.

The heart in dermatomyositis and polymyositis

Discussion

Member takes

Implication

Key Points

Cite This Study

The heart in dermatomyositis and polymyositis

Discussion

Member takes

Implication

Key Points

Cite This Study

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