Key result
Subclinical cardiac involvement in autoimmune myositis and MCTD drives mortality primarily via conduction abnormalities.
Why the study?
Cardiac involvement in idiopathic inflammatory myopathies and mixed connective tissue disease is often subclinical and may be overlooked despite being a major cause of death.
Population
Patients with idiopathic inflammatory myopathies, juvenile dermatomyositis, and mixed connective tissue disease
Design
Review
Authors
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Subclinical conduction abnormalities predominate in myositis; leaves open whether ECG screening improves prognosis or warrants intervention.
Cardiac involvement in myositis and MCTD is often subclinical but constitutes a major cause of death, warranting clinical attention.
Ingrid E. Lundberg (2005) conducted a review in Autoimmune myositis and mixed connective tissue disease. Cardiac involvement in autoimmune myositis and mixed connective tissue disease is often subclinical but constitutes a major cause of death, primarily presenting as conduction abnormalities.
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