Why the study?
Do different antihypertensive agents have varying effects on blood pressure and hemodynamics during exercise in patients with untreated essential hypertension?
Population
64 patients with untreated essential hypertension (WHO I, II), mean age 49+/-10 years.
Comparison
4 weeks of treatment with metoprolol, doxazosin… vs Baseline (before treatment)
Design
Cohort
Follow-up
4 weeks
Authors
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May guide antihypertensive selection in active patients by exercise BP response; hypothesis-generating and requires randomized confirmation.
Do different antihypertensive agents have varying effects on blood pressure and hemodynamics during exercise in patients with untreated essential hypertension?
Antihypertensive agents differ in their effects on exercise hemodynamics, suggesting that blood pressure during exercise should be considered when selecting medications for highly active patients.
Arita et al. (2001) studied this question.
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