THE MALARIA PARASITE t= pre-erythrocytic development of the parasites takes place in the parenchymal cells of the liver with the production of merozoites which invade the erythrocytes to establish the blood infection.At the same time strong evidence has been adduced to suggest that this developmental cycle in the liver persists after the establishment of the erythrocytic infection, may even exist without the latter, is relatively unaffected by the immunity response of the host, and is the probable sburce of relapses of the disease.
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WR Heath (1950) studied this question.