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January 1, 1999HypertensionOpen Access

Effects of Smoking Cessation on Blood Pressure and Heart Rate Variability in Habitual Smokers

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Why the study?

Does 1-week smoking cessation improve ambulatory blood pressure and heart rate variability in normotensive male habitual smokers?

Population

39 normotensive male habitual smokers, mean age 32.5+/-1.0 years

Comparison

1-week smoking cessation vs 1-week smoking period

Design

RCT, The order of the 2 periods was randomized

Follow-up

1 week per period

Authors

JMJunichi MinamiTIToshihiko IshimitsuHMHiroaki Matsuoka

Discussion

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Overview

Supports recommending brief smoking cessation to lower ambulatory BP in normotensive smokers; extends causal evidence beyond observational data.

Structured PICO

Does 1-week smoking cessation improve ambulatory blood pressure and heart rate variability in normotensive male habitual smokers?

P
Population
39 normotensive male habitual smokers, mean age 32.5+/-1.0 years
I
Intervention
1-week smoking cessation
C
Comparator
1-week smoking period (smoking cigarettes according to usual patterns)
O
Outcome
Ambulatory blood pressure, heart rate, and heart rate variability (pNN50, LF, HF components) measured over 24 hourssurrogate

One week of smoking cessation immediately and significantly reduces ambulatory blood pressure and heart rate while improving heart rate variability in normotensive male smokers.

Cite This Study

Minami et al. (1999) studied this question.

synapsesocial.com/papers/6a70d8208031ec7bb1dc9ef2https://doi.org/10.1161/01.hyp.33.1.586
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A controlled study of the autonomic changes produced by habitual cigarette smoking in healthy subjects1996 · 103 citations
  2. 2Mechanisms responsible for sympathetic activation by cigarette smoking in humans.1994 · 394 citations
  3. 3Elevation of Ambulatory Systolic Blood Pressure in Hypertensive Smokers1991 · 241 citations
  4. 4Norepinephrine and Epinephrine Release and Adrenergic Mediation of Smoking-Associated Hemodynamic and Metabolic Events1976 · 1,112 citations
  5. 5Cigarette Smoking Increases Sympathetic Outflow in Humans1998 · 340 citations