July 1, 1983The Journal of General PhysiologyOpen Access

Birefringence signals in mammalian and frog myocardium. E-C coupling implications.

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Population

Mammalian and frog myocardium (heart muscles)

Design

Preclinical

Authors

RWRichard E. WeissUniversity of California, Los Angeles MMMartin MoradElectrophysiology

Discussion

Member takes

Implication

May advance optical probes of SR Ca2+ release in animal models; leaves open human translation.

Structured PICO

Population

Mammalian and frog myocardium (heart muscles)

Intervention

Inotropic interventions including variation of extracellular Ca2+, stimulation frequency, temperature, epinephrine, and caffeine (2-10 mM)

Outcome

Birefringence signals (components and time course)surrogate

The study identifies a specific component of birefringence signals in mammalian myocardium that correlates with sarcoplasmic reticulum calcium release during excitation-contraction coupling.

Cite This Study

Weiss et al. (1983) studied this question.

synapsesocial.com/papers/6a70d895a528af2d65c3c66e https://doi.org/10.1085/jgp.82.1.79

View Full Paper

Ask AI

Bookmark

Birefringence signals in mammalian and frog myocardium. E-C coupling implications.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Birefringence signals in mammalian and frog myocardium. E-C coupling implications.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider