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August 1, 2014Journal of neurosurgery

What clinical factors predict the incidence of deep venous thrombosis and pulmonary embolism in neurosurgical patients?

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Population

38,058 neurosurgical cases from the American College of Surgeons National Surgical Quality Improvement…

Design

Cohort

Follow-up

30 days

Authors

JRJohn D. RolstonBrigham and Women's HospitalSHSeunggu J. HanStanford UniversityOBOrin BlochNorthwestern University

Discussion

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Overview

Supports VTE prophylaxis tailoring in cranial neurosurgery; leaves open prospective validation of predictors.

Structured PICO

P
Population
38,058 neurosurgical cases (extracted from a total database of 1,777,035 patients) from the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database between 2006 and 2011 across 47 US states.
O
Outcome
Incidence of venous thromboembolism (VTE), including deep venous thrombosis (DVT) requiring treatment or pulmonary embolism (PE), within 30 days of an operation.hard clinical

Venous thromboembolism occurs in 1.7% of neurosurgical patients, with cranial procedures, ventilator dependence, immobility, chronic steroid use, and sepsis identified as significant independent predictors.

Cite This Study

Rolston et al. (2014) studied this question.

synapsesocial.com/papers/6a70dbbee36a167817e2aef3https://doi.org/10.3171/2014.6.jns131419
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Low Molecular Weight Heparin and Compression Stockings in the Prevention of Venous Thromboembolism in Neurosurgery1996 · 243 citations
  2. 2Enoxaparin plus Compression Stockings Compared with Compression Stockings Alone in the Prevention of Venous Thromboembolism after Elective Neurosurgery1998 · 523 citations
  3. 3Prophylaxis for Venous Thromboembolism: A Great Global Divide between Expert Guidelines and Clinical Practice?2012 · 22 citations
  4. 4Successful Implementation of the Department of Veterans Affairs’ National Surgical Quality Improvement Program in the Private Sector: The Patient Safety in Surgery Study2008 · 558 citations