Why the study?
Does a biodegradable PLA stent coating with PEG-hirudin and iloprost reduce thrombus formation in an ex vivo human stasis model?
Population
Ex vivo human stasis model using whole blood
Comparison
Steel and gold-surface stents coated with… vs Bare steel and bare gold-surface stents, and an…
Design
Preclinical
Follow-up
90 days (in-vitro studies)
Authors
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May inform coated stent design to limit thrombosis; leaves open translation to clinical outcomes in patients.
Does a biodegradable PLA stent coating with PEG-hirudin and iloprost reduce thrombus formation in an ex vivo human stasis model?
A biodegradable stent coating releasing PEG-hirudin and iloprost effectively reduces thrombus formation in an ex vivo model.
Herrmann et al. (1999) studied this question.
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