Population
52 patients with hypertrophic cardiomyopathy and 40 healthy, age and sex matched controls.
Design
Case-control
Authors
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Autoantibodies associate with autonomic and repolarization changes in HCM; hypothesis-generating and should not yet change practice.
The presence of autoantibodies against beta1 and/or Muscarin-2 receptors in HCM patients is associated with more severe clinical manifestations, including altered heart rate variability and increased wall thickness.
Peukert et al. (1999) studied this question.