Why the study?
Does cardiac magnetic resonance improve left ventricular characterization and surgical timing in patients with primary degenerative mitral regurgitation?
Does cardiac magnetic resonance improve left ventricular characterization and surgical timing in patients with primary degenerative mitral regurgitation?
CMR has potential for better LV characterization in primary mitral regurgitation, but further research is needed to establish CMR-based thresholds for surgical timing.
A fifth of patients with primary degenerative mitral regurgitation continue to present with de novo ventricular dysfunction following surgery and higher rates of heart failure, morbidity, and mortality. This raises questions as to why the left ventricle (LV) might fail to recover and has led to support for better LV characterization; cardiac magnetic resonance (CMR) may play a role in this regard, pending further research and outcome data. CMR has widely acknowledged advantages, particularly in repeatability of measurements of volume and ejection fraction, yet recent guidelines relegate its use to cases where there is discordant information or poor-quality imaging from echocardiography because of the lack of data regarding the CMR-based ejection fraction threshold for surgery and CMR-based outcome data. This article reviews the current evidence regarding the role of CMR in an integrated surveillance and surgical timing programme.
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Liu et al. (2018) studied this question.
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