Why the study?
Does phentolamine infusion alter active and inactive renin release in patients with unilateral renal artery stenosis?
Population
5 patients with unilateral renal artery stenosis
Design
Case_series
Authors
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Phentolamine may increase renin release from stenosed kidneys; this case report leaves open intrarenal alpha-adrenoreceptor involvement in renovascular hypertension.
Does phentolamine infusion alter active and inactive renin release in patients with unilateral renal artery stenosis?
Phentolamine infusion stimulates active and inactive renin release specifically from the stenosed kidney in patients with renovascular hypertension, suggesting a role for intrarenal alpha-adrenoreceptors.
Pedrinelli et al. (1983) studied this question.
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