High Resolution NMR Studies of DNA Hairpins with Four Nucleotides in the Loop Region

When considering DNA structure the first picture that comes to mind is that of the celebrated double helix. Notwithstanding the overwhelming importance of this structure it is interesting however that refined structural studies that have been conducted during the last ten years have demonstrated that deviations, at the nucleotide level, from the idealized double helix and its consonant symmetry properties may lead to very interesting global structural variations.