What question did this study set out to answer?

To evaluate the quality of evidence underlying clinical practice guidelines in anesthesiology and examine how clinicians and policymakers should interpret these recommendations.

May 27, 2021AnesthesiologyOpen Access

Clinical Practice Guidelines in Anesthesiology: Adjusting Our Expectations

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Design

Editorial

Authors

MNMark D. NeumanRutgers, The State University of New Jersey JAJeffrey L. ApfelbaumTulane University

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Implication

This editorial highlights the need for more high-quality randomized trials in perioperative care and cautions against over-reliance on guideline recommendations based on low-level evidence.

Key Points

To evaluate the quality of evidence underlying clinical practice guidelines in anesthesiology and examine how clinicians and policymakers should interpret these recommendations.
Analyzed 2,280 recommendations from 60 clinical practice guidelines published by 26 anesthesia societies in North America and Europe over a 10-year period.
Evaluated the level of evidence supporting each recommendation and compared evidence quality against the rigor of the guideline development process (including GRADE and Delphi methods).
Half (50%) of all 2,280 recommendations were derived from the lowest level of evidence evaluated, consisting primarily of case reports or expert consensus.
Fewer than 1 in 6 recommendations (<16.7%) were supported by the highest level of evidence from multiple randomized controlled trials or meta-analyses.
The proportion of recommendations grounded in lower-level evidence did not change over the 10-year period and did not differ by guideline development rigor or transparency standards.

Cite This Study

Neuman et al. (2021) studied this question.

synapsesocial.com/papers/6a70e722febe604dd709ab74 https://doi.org/10.1097/aln.0000000000003809

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Implication

This editorial highlights the need for more high-quality randomized trials in perioperative care and cautions against over-reliance on guideline recommendations based on low-level evidence.

Clinical Practice Guidelines in Anesthesiology: Adjusting Our Expectations

Discussion

Member takes

Implication

Key Points

Cite This Study

Clinical Practice Guidelines in Anesthesiology: Adjusting Our Expectations

Discussion

Member takes

Implication

Key Points

Cite This Study

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