Why the study?
Does a 30-second balloon inflation protocol improve acute angiographic results or tolerability compared to a 60-second protocol in patients undergoing PTCA?
Does a 30-second balloon inflation protocol improve acute angiographic results or tolerability compared to a 60-second protocol in patients undergoing PTCA?
A 30-second balloon inflation during PTCA is as effective as a 60-second inflation for angiographic success but is significantly better tolerated by patients.
30-second inflations match 60-second ones for angiographic success with less pain; supports shorter protocols in routine PTCA.
This study was performed to evaluate the importance of the duration of balloon inflation during PTCA, by comparing two common inflation durations. Patients were randomized to a 30-second inflation protocol (group I, 83 procedures, 109 lesions), or a 60-second protocol (group II, 83 procedures, 115 lesions). There were no differences in baseline characteristics between the two groups, and no subsequent differences in mean inflation number (3.4 +/- 1.6 vs 3.1 +/- 1.6), residual stenosis (34% +/- 17% vs 33% +/- 16%), presence of dissection (29% vs 34%), or clinical success (89% vs 84%), group I versus group II, respectively. The 30-second inflations caused significantly less chest pain score (147 +/- 239 vs 399 +/- 516, P less than 0.001), and ST segment alteration (75 +/- 94 seconds vs 136 +/- 163, P less than 0.05). These results indicate that 60-second inflations do not produce a superior result to 30-second inflations. Furthermore, shorter inflations are much better tolerated.
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Garrahy et al. (1991) studied this question.
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