Why the study?
Pulmonary embolism rarely compromises the left ventricular ejection fraction, prompting this report on its association with left ventricular systolic dysfunction via the reverse Bernheim effect.
This case highlights the rare presentation of an acute saddle pulmonary embolus causing profound left ventricular systolic dysfunction via the reverse Bernheim effect.
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Acute saddle PE with clot-in-transit may impair LV function; single case leaves causality and frequency open.
Pulmonary embolism is a life-threatening medical emergency associated with right ventricular failure. Rarely, it impacts the left ventricle to the point of compromising the left ventricular (LV) ejection fraction. We present a case of a 73-year-old African American male with a medical history pertinent for intravascular large B-cell lymphoma who developed an acute saddle embolus with a "clot-in-transit" and profound LV systolic dysfunction. Our report illustrates how an acute saddle embolus may be associated with LV systolic dysfunction via the "reverse Bernheim effect." Additionally, the report highlights the significance of a "clot-in-transit" and LV systolic dysfunction, as they both directly correlate with increased risk of mortality.
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Doodnauth et al. (2022) studied this question.
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