Key result
Fibrinolytic therapy successfully treats PE and thrombus in transit, improving ventricular systolic function and strain.
Case Report (n=1)
No
Fibrinolytic therapy successfully improved right ventricular function in a patient with pulmonary embolism and a thrombus in transit.
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May support fibrinolysis in select PE with thrombus in transit; hypothesis-generating and requires prospective validation.
A clinical case is presented at the Hospital Centenario Miguel Hidalgo with a diagnosis of pulmonary thromboembolism with a thrombus in transit and dysfunction of the right cavities, secondary to immobilization due to a history of previous spinal surgery as an ankylosing spondylitis treatment. He was admitted to the emergency room with typical symptoms of the entity, evidenced by angiotomography, later a transthoracic echocardiogram was performed, presenting the characteristic echocardiographic signs of right ventricular dysfunction and evidence of mobile thrombus in the right cavities, for which reason fibrinolytic therapy was decided with success, evidenced in transthoracic echocardiography with improvement of ventricular systolic function and strain.
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Ugalde et al. (2023) conducted a case report in Pulmonary thromboembolism with a thrombus in transit and right ventricular dysfunction (n=1). Fibrinolytic therapy was evaluated on Improvement of ventricular systolic function and strain. Fibrinolytic therapy successfully treated a patient with pulmonary thromboembolism and a thrombus in transit, improving ventricular systolic function and strain.
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