Population
Patients suffering a major bleeding event while receiving oral anticoagulants
Design
Review
Authors
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May inform emergency protocols for these agents; leaves open need for randomized validation of reversal strategies.
Provides a review of emergency management strategies for bleeding associated with novel oral anticoagulants, emphasizing supportive care for most cases and clotting-factor substitutes for severe hemorrhage.
Peacock et al. (2012) studied this question.
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