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Highlights that despite the widespread use of DOACs, certain clinical scenarios still necessitate the use of older antithrombotics or dose modifications.
Direct oral anticoagulants (DOACs) are used in Europe over a decade. One of their favourable properties is a stable prophylactic or therapeutic drug dose. Sometimes, however, it is preferred to use older antithrombotic drugs (vitamin K antagonists, heparins) or -in some clinical situations -to modify the standard recommended drug dose.
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Jacek Musiał (2022) studied this question.
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