Why the study?
Does insulin play a permissive role for the vasoactive effect of GIP regulating adipose tissue metabolism in healthy lean humans?
Population
6 lean healthy subjects
Comparison
Glucose-dependent insulinotropic polypeptide… vs GIP infusion in combination with…
Design
Other
Authors
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Exploratory study in lean volunteers; leaves open insulin and C-peptide dependence of GIP effects on adipose perfusion in metabolic disease.
Does insulin play a permissive role for the vasoactive effect of GIP regulating adipose tissue metabolism in healthy lean humans?
Insulin is permissive for GIP to induce an increase in blood flow and triglyceride clearance in subcutaneous abdominal adipose tissue in healthy lean humans, independent of C-peptide.
Asmar et al. (2016) studied this question.
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