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March 1, 1990Journal of Neurology Neurosurgery & PsychiatryOpen Access

Stroke risk and critical carotid stenosis.

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Why the study?

Is there a critical degree of carotid stenosis at which stroke risk becomes maximal in patients with asymptomatic carotid bruits?

Population

500 patients with asymptomatic carotid bruits

Design

Cohort

Authors

JNJohn W. NorrisRutgers, The State University of New JerseyCZChengcheng ZhuJiangsu University

Discussion

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Implication

Peak events at 75-90% stenosis may flag higher-risk patients; leaves open whether thresholds for intervention warrant prospective testing.

Structured PICO

Is there a critical degree of carotid stenosis at which stroke risk becomes maximal in patients with asymptomatic carotid bruits?

P
Population
500 patients with asymptomatic carotid bruits
O
Outcome
Risk of ischaemic cerebral events and progression of the arterial lesionhard clinical

Stroke risk in asymptomatic carotid stenosis is not strictly linear but peaks at 75-90% stenosis, suggesting a critical window for therapeutic intervention.

Cite This Study

Norris et al. (1990) studied this question.

synapsesocial.com/papers/6a70f1c4a528af2d65c3d435https://doi.org/10.1136/jnnp.53.3.235
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The natural history of carotid arterial disease in asymptomatic patients with cervical bruits.1984 · 535 citations
  2. 2Carotid artery stenosis - hemodynamic significance and clinical course1981 · 119 citations
  3. 3Carotid Artery Stenosis—Hemodynamic Significance and Clinical Course1981 · 105 citations
  4. 4Outcome in Patients with Asymptomatic Neck Bruits1986 · 546 citations
  5. 5Quantitation of carotid stenosis with continuous-wave (C-W) Doppler ultrasound.1979 · 359 citations