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January 1, 2019Journal of Cardiovascular Magnetic ResonanceOpen Access

Quantification of aortic pulse wave velocity from a population based cohort: a fully automatic method

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Why the study?

Aortic pulse wave velocity predicts adverse cardiovascular events and can be assessed non-invasively by MRI, but requires automated methods for large population-based cohorts.

Does a fully automatic method accurately quantify aortic pulse wave velocity compared to manual analysis in subjects undergoing MRI?

Population

212 subjects from a multi-center heart-brain connection cohort

Comparison

Novel automatic method vs manual analysis for PWV quantification

Design

Retrospective multi-center cohort study

Authors

RSRahil ShahzadUniversity of CologneASArun ShankarPallium IndiaRARaquel P. AmierAmsterdam University Medical Centers

Discussion

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Implication

MRI-based aortic PWV supports risk stratification in observational cohorts; leaves open prospective validation before routine clinical use.

Structured PICO

Does a fully automatic method accurately quantify aortic pulse wave velocity compared to manual analysis in subjects undergoing MRI?

P
Population
212 subjects retrospectively selected from a large multi-center heart-brain connection cohort
I
Intervention
Fully automatic method to quantify aortic pulse wave velocity (PWV) using multi-slice 3D and 2D velocity encoded MRI scans
C
Comparator
Manual analysis of MRI scans
O
Outcome
Difference in aortic length and computed PWV between automatic and manual methodssurrogate

A fully automatic method for quantifying aortic pulse wave velocity from MRI scans shows very good agreement with manual analysis, offering a scalable solution for large population-based studies.

Cite This Study

Shahzad et al. (2019) studied this question.

synapsesocial.com/papers/6a70f24b35aa2c282ce246d2https://doi.org/10.1186/s12968-019-0530-y

Topics

Women and heart disease
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Heart-Brain Connection: A Multidisciplinary Approach Targeting a Missing Link in the Pathophysiology of Vascular Cognitive Impairment2014 · 59 citations
  2. 2Measurement of aortic arch pulse wave velocity in cardiovascular MR: Comparison of transit time estimators and description of a new approach2011 · 78 citations
  3. 3Review of MRI-based measurements of pulse wave velocity: a biomarker of arterial stiffness.2014 · 168 citations
  4. 4Aortic Arch Pulse Wave Velocity Assessed by Magnetic Resonance Imaging as a Predictor of Incident Cardiovascular Events2017 · 88 citations
  5. 5Age‐related and regional changes of aortic stiffness in the marfan syndrome: Assessment with velocity‐encoded MRI2011 · 61 citations