The E to F slope on echocardiography is not a fixed value in mitral stenosis and can appear normal under certain conditions such as altered heart rate.
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E to F slope in mitral stenosis warrants heart-rate context for interpretation; case report leaves open its reliability as a fixed parameter.
A patient with mitral stenosis and atrial flutter was found to have a normal diastolic closure rate (E to F slope). Following cardioversion, the typical echocardiographic features of mitral stenosis were found. After various interventions that increased heart rate, however, the diastolic closure rate increased. This report demonstrates, therefore, that the E to F slope is not always a fixed value in mitral stenosis and that under certain conditions it may even appear to be normal.
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Ambrose et al. (1979) studied this question.
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