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Readmitting potassium to potassium-deprived mouse liver segments during intracellular microelectrode recording caused an increase in membrane potential and a gradual reduction in amplitude of electrotonic potentials set up by current pulses applied to another liver cell some distance away. Readmitting K in a high concentration (100 mM) caused a transient hyperpolarization followed by depolarization. The transient hyperpolarization was abolished by Strophanthin-G.
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Graf et al. (1974) studied this question.
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