Why the study?
Does left atrial appendage occlusion with the Amplatzer Amulet device provide effective LAA sealing and acceptable safety in patients with atrial fibrillation and contraindication to oral anticoagulation?
Does left atrial appendage occlusion with the Amplatzer Amulet device provide effective LAA sealing and acceptable safety in patients with atrial fibrillation and contraindication to oral anticoagulation?
LAA occlusion with the Amplatzer Amulet device provides high procedural success and excellent LAA sealing, though procedure-related complications remain a challenge.
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Amulet LAAO feasible in this AF cohort; leaves open comparative efficacy and safety versus other devices.
Kleinecke et al. (2017) studied this question.
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