Left Ventricular Thrombus and Subsequent Thromboembolism, Comparison of Anticoagulation, Surgical Removal, and Antiplatelet Agents
Why the study?
Do different treatment strategies (anticoagulation, operative treatment, antiplatelet agents) affect the rate of systemic thromboembolism in patients with left ventricular thrombus?
Population
62 patients with left ventricular thrombus diagnosed between May 2003 to November 2011.
Comparison
Anticoagulation, operative treatment, or… vs Comparison among the three treatment groups
Design
Cohort
Authors
Discussion
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Member takes
Implication
Does not support changing anticoagulation for left ventricular thrombus; leaves open whether operative treatment reduces thromboembolism risk.
Structured PICO
Do different treatment strategies (anticoagulation, operative treatment, antiplatelet agents) affect the rate of systemic thromboembolism in patients with left ventricular thrombus?
P
Population
62 patients with left ventricular (LV) thrombus (80.6% ischemic etiology) diagnosed between May 2003 to November 2011.
I
Intervention
Anticoagulation, operative treatment (surgical removal), or antiplatelet agents
C
Comparator
Comparison among the three treatment groups
O
Outcome
Systemic thromboembolism (post-treatment)hard clinical
In patients with left ventricular thrombus, the rate of post-treatment systemic thromboembolism did not differ significantly between anticoagulation, operative treatment, and antiplatelet agents, though operative treatment showed a trend toward fewer events.
Cite This Study
Lee et al. (2012) studied this question.