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September 1, 2013Acta Physiologica Hungarica

Corrected QT interval in white young healthy women: Should the norms be updated?

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Why the study?

How do different QTc formulae affect the calculated QTc duration in young healthy women?

Population

138 white young healthy Slovak women, aged 18-24 years

Comparison

Calculation of QTc duration using nine different… vs Comparison among the different QTc formulae

Design

Cross-sectional

Authors

SKS KujaníkUniversity of Pavol Jozef ŠafárikJPJ PetrovičováUniversity of Pavol Jozef Šafárik

Discussion

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Implication

QTc values in young healthy women vary substantially by formula; leaves open whether population-specific norms are warranted.

Structured PICO

How do different QTc formulae affect the calculated QTc duration in young healthy women?

P
Population
138 white young healthy Slovak women, aged 18-24 years
I
Intervention
Calculation of QTc duration using nine different formulae (including Bazett, Fridericia, Hodges, Rautaharju and Arrowood, Framingham-Sagie, Lecocq, Sarma, and Malik)
C
Comparator
Comparison among the different QTc formulae
O
Outcome
QTc duration and dispersionsurrogate

Different QTc formulae yield significantly different values in healthy young women, suggesting that population-specific formulae should be used and current norms updated.

Cite This Study

Kujaník et al. (2013) studied this question.

synapsesocial.com/papers/6a71015fe36a167817e2d6d0https://doi.org/10.1556/aphysiol.100.2013.3.2
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Modulation of the QT interval: effects of graded exercise and reflex cardiovascular stimulation1993 · 33 citations
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  4. 4Cut-Offs for Screening Prolonged QT Intervals From Fridericia's Formula in Children and Adolescents2010 · 45 citations
  5. 5Ionic, molecular, and cellular bases of QT-interval prolongation and torsade de pointes2007 · 185 citations