Why the study?
Does rapid saline infusion cause sustained secretion of atrial natriuretic hormone independent of atrial stretch in normal men?
Population
11 normal men
Comparison
Rapid infusion of 1 L 150 mmol/L NaCl vs Baseline values (pre-infusion)
Follow-up
90 minutes
Authors
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Persistent ANH elevation after saline occurs beyond atrial pressure normalization; leaves open stretch-independent regulatory mechanisms.
Does rapid saline infusion cause sustained secretion of atrial natriuretic hormone independent of atrial stretch in normal men?
Sustained secretion of atrial natriuretic hormone following saline infusion is not maintained by atrial stretch, suggesting other regulatory mechanisms.
Dananberg et al. (1989) studied this question.
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