Why the study?
Neoplasmatic disease increases acute pulmonary embolism risk through thrombotic mechanisms, and the role of active and occult cancer in venous thromboembolism prevalence has been increasingly discussed.
Does the presence of active or recent cancer increase the risk of death and secondary APE in patients with acute pulmonary embolism?
Population
366 consecutive patients with a diagnosis of APE
Comparison
Concomitant active cancer or cancer within 5 years vs no concomitant active malignancy or cancer history
Design
Retrospective medical records study
Authors
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Cancer in APE may worsen prognosis, especially lung; leaves open whether screening improves outcomes in observational cohorts.
Does the presence of active or recent cancer increase the risk of death and secondary APE in patients with acute pulmonary embolism?
In patients with acute pulmonary embolism, the presence of cancer is associated with a more than three-fold increased risk of death and recurrent APE.
Feusette et al. (2023) studied this question.
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