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What proportion of the Norwegian population is classified as high risk for cardiovascular disease according to the 2003 European guidelines?
What proportion of the Norwegian population is classified as high risk for cardiovascular disease according to the 2003 European guidelines?
Implementation of the 2003 European guidelines would classify the vast majority of adult Norwegians as being at high risk for fatal cardiovascular disease, highlighting potential overestimation of risk or need for population-specific calibration.
May overestimate risk in Norwegians; leaves open need for population-specific guideline calibration.
OBJECTIVE: To estimate the high risk group for cardiovascular disease in a well defined Norwegian population according to European guidelines and the systematic coronary risk evaluation system. DESIGN: Modelling study. SETTING: Nord-Tröndelag health study 1995-7 (HUNT 2), Norway. PARTICIPANTS: 5548 participants of the Nord-Tröndelag health study 1995-7, aged 40, 50, 55, 60, and 65. MAIN OUTCOME MEASURES: Distribution of risk categories for cardiovascular disease, with emphasis on the high risk group. MAIN RESULTS: At age 40, 22.5% (95% confidence interval 19.3% to 25.7%) of women and 85.9% (83.2% to 88.6%) of men were at high risk of cardiovascular disease. Corresponding numbers at age 50 were 39.5% (35.9% to 43.1%) and 88.7% (86.3% to 91.0%) and at age 65 were 84.0% (80.6% to 87.4%) and 91.6% (88.6% to 94.1%). At age 40, one out of 10 women and no men would be classified at low risk for cardiovascular disease. CONCLUSION: Implementation of the 2003 European guidelines on prevention of cardiovascular disease in clinical practice would classify most adult Norwegians at high risk for fatal cardiovascular disease.
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Getz et al. (2005) studied this question.
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