Why the study?
How do different cardiovascular risk algorithms and cut-off levels affect the proportion of a middle-aged population targeted for primary prevention?
How do different cardiovascular risk algorithms and cut-off levels affect the proportion of a middle-aged population targeted for primary prevention?
The choice of cardiovascular risk algorithm and cut-off level drastically alters the size of the population targeted for primary prevention, highlighting the need to consider resource allocation and medicalization when drafting guidelines.
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Varying SCORE cut-offs produce large sex-specific disparities in primary prevention eligibility; leaves open optimal thresholds for efficient, equitable guidelines.
Brekke et al. (2007) studied this question.