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March 1, 2001Perfusion

Emergency redo mitral valve replacement in a 27-year-old pregnant female with a clotted prosthetic mitral valve, preoperative fetal demise and postoperative ventricular assist device: a case report

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Population

27-year-old pregnant Laotian woman at 16 weeks gestation with a clotted St Jude mechanical mitral valve…

Design

Case_report

Follow-up

7 months (3 months in hospital, 4 months post-discharge)

Authors

DODawn OlesRBRichard G. BerryessaKCKelly CampbellCalifornia State University, San Bernardino

Discussion

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Implication

Highlights fatal thrombosis and hemorrhage risks with anticoagulation bridging in pregnant mechanical valve patients; leaves open optimal strategies for prospective study.

Structured PICO

P
Population
27-year-old pregnant Laotian woman (n=1) at 16 weeks gestation with a clotted St Jude mechanical mitral valve following a switch from warfarin to enoxaparin, and preoperative fetal demise.
I
Intervention
Emergency redo mitral valve replacement (27 mm St Jude valve) followed by right ventricular assist device (RVAD) support for 2 days.
O
Outcome
Clinical course and survivalhard clinical

This case highlights the severe, life-threatening risks of mechanical valve thrombosis during pregnancy when bridging anticoagulation, as well as the fatal bleeding risks associated with subsequent anticoagulation management.

Cite This Study

Oles et al. (2001) studied this question.

synapsesocial.com/papers/6a710bb426a7f98052dd78f7https://doi.org/10.1177/026765910101600211

Topics

Mechanical circulatory support
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Prosthetic Heart Valve and Pregnancy2010 · 25 citations
  2. 2Cardiac valve prostheses, anticoagulation, and pregnancy.1986 · 50 citations
  3. 3Pregnancy in patients after valve replacement.1976 · 71 citations
  4. 4Dose-dependent fetal complications of warfarin in pregnant women with mechanical heart valves1999 · 494 citations
  5. 5Efficacy of low‐dose, subcutaneously administered heparin in treatment of pregnant women with artificial heart valves1983 · 35 citations