June 20, 2018Cardiology JournalOpen Access

Time-to-effect guided pulmonary vein isolation utilizing the third-generation versus second generation cryoballoon: One year clinical success

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Why the study?

Does third-generation cryoballoon (CB3) improve 1-year clinical success compared to second-generation cryoballoon (CB2) in patients with paroxysmal or short-standing persistent atrial fibrillation?

Population

110 consecutive patients with paroxysmal or short-standing persistent atrial fibrillation (AF)

Comparison

Third-generation cryoballoon based pulmonary… vs Second-generation cryoballoon based pulmonary…

Design

Cohort

Follow-up

median 409 days (CB3) and 432 days (CB2)

Authors

CHChristian‐Hendrik HeegerElectrophysiology CSChristopher SchuetteAsklepios Klinik St. Georg VSValentina SeitelbergerLudwig-Maximilians-Universität München

Discussion

Member takes

Implication

No outcome benefit with CB3 despite more real-time signals; leaves open value of TTE-guided ablation strategies.

Structured PICO

Does third-generation cryoballoon (CB3) improve 1-year clinical success compared to second-generation cryoballoon (CB2) in patients with paroxysmal or short-standing persistent atrial fibrillation?

Population

110 consecutive patients with paroxysmal or short-standing persistent atrial fibrillation (AF)

Intervention

Third-generation cryoballoon (CB3) based pulmonary vein isolation (n=55), with freeze-cycle duration set to time-to-effect (TTE) + 120 s if TTE could be recorded, otherwise a fixed freeze-cycle duration of 180 s

Comparator

Second-generation cryoballoon (CB2) based pulmonary vein isolation (n=55), with freeze-cycle duration set to time-to-effect (TTE) + 120 s if TTE could be recorded, otherwise a fixed freeze-cycle duration of 180 s

Outcome

1-year clinical success (remaining in stable sinus rhythm after a single procedure)hard clinical

The third-generation cryoballoon improves real-time pulmonary vein isolation visualization compared to the second-generation device, but does not significantly improve 1-year clinical success rates in patients with atrial fibrillation.

Cite This Study

Heeger et al. (2018) studied this question.

synapsesocial.com/papers/6a710cb078a11c550e0b1647 https://doi.org/10.5603/cj.a2018.0056

Topics

Persistent AF management Atrial fibrillation AF ablation outcomes

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Time-to-effect guided pulmonary vein isolation utilizing the third-generation versus second generation cryoballoon: One year clinical success

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Time-to-effect guided pulmonary vein isolation utilizing the third-generation versus second generation cryoballoon: One year clinical success

Discussion

Member takes

Implication

Structured PICO

Cite This Study

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Topics

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