Why the study?
Does submaximal neuromuscular electrical stimulation reveal peripheral abnormalities contributing to impaired contracting skeletal muscle oxygenation in nonhypoxemic, moderate-to-severe COPD patients compared to controls?
Population
15 nonhypoxemic patients with moderate-to-severe COPD and 10 age- and gender-matched sedentary controls.
Comparison
Submaximal neuromuscular electrical stimulation… vs Age- and gender-matched sedentary controls…
Design
Case-control
Authors
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May support NMES to probe peripheral oxygenation deficits in COPD; leaves open translation to targeted interventions.
Does submaximal neuromuscular electrical stimulation reveal peripheral abnormalities contributing to impaired contracting skeletal muscle oxygenation in nonhypoxemic, moderate-to-severe COPD patients compared to controls?
Peripheral abnormalities contribute mechanistically to impaired contracting skeletal muscle oxygenation in nonhypoxemic, moderate-to-severe COPD patients, independent of central cardiorespiratory constraints.
Medeiros et al. (2014) studied this question.
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