Why the study?
Does endotoxic shock cause central-to-peripheral vascular tone decoupling in a porcine model?
Does endotoxic shock cause central-to-peripheral vascular tone decoupling in a porcine model?
Central-to-peripheral vascular tone decoupling during endotoxic shock may explain the inaccuracy of peripheral arterial pressure-based cardiac output algorithms in sepsis.
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May explain peripheral CO monitoring errors in sepsis; leaves open translation to human endotoxemia.
Hatib et al. (2011) studied this question.
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