Population
Patients with clinical anxiety disorders, including panic disorder and Generalized Anxiety Disorder
Design
Review
Authors
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Should not yet change anxiety management; leaves open direct testing of noradrenergic hypotheses in panic disorder and GAD.
This review summarizes the indirect clinical evidence supporting the role of central noradrenergic dysregulation across various anxiety disorders.
Kalk et al. (2010) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: