Population
Frog heart ventricle preparations
Comparison
Changes in extra- and intracellular pH vs Baseline/normal pH conditions
Design
Preclinical
Authors
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Acidosis may impair myocardial contractility; leaves open translation to mammalian models and clinical acid-base management.
Changes in extra- and intracellular pH significantly alter the mechanical and electrical activity of frog heart ventricle preparations, affecting twitch tension and potassium contractures.
H. Lorković (1966) studied this question.
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