Why the study?
Does maternal diabetes increase the risk of specific cardiovascular malformations in infants?
Population
2,259 mothers of infants with cardiovascular malformations and 2,801 mothers of controls from the…
Comparison
Maternal diabetes vs Mothers without diabetes
Design
Case-control
Authors
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May prompt closer fetal echocardiography surveillance in overt diabetes; hypothesis-generating for causal confirmation and prevention trials.
Does maternal diabetes increase the risk of specific cardiovascular malformations in infants?
Overt maternal diabetes is strongly associated with specific conotruncal cardiovascular malformations, specifically double outlet right ventricle and truncus arteriosus.
Ferencz et al. (1990) studied this question.
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