Why the study?
Does maternal pre-existing diabetes increase the risk of cardiovascular malformations in infants?
Population
192,618 live births in one health region over six years, including 609 infants of mothers with pre-existing…
Comparison
Maternal pre-existing diabetes vs Non-diabetic mothers
Design
Cohort
Follow-up
at live birth
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Maternal pre-existing diabetes was associated with fivefold higher cardiovascular malformation risk; confirms association but leaves open optimal prevention strategies.
Does maternal pre-existing diabetes increase the risk of cardiovascular malformations in infants?
Pre-existing maternal diabetes is associated with a fivefold increased risk of cardiovascular malformations in infants, particularly transposition of the great arteries, truncus arteriosus, and tricuspid atresia.
A 2003 study studied this question.
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