Why the study?
Does the use of centrifugal pumps compared to roller pumps reduce damage to blood elements and coagulation system activation in patients undergoing open heart surgery?
Population
29 patients undergoing open heart surgery requiring cardiopulmonary bypass (CPB)
Comparison
Centrifugal pumps used as the main pump for… vs Roller pump used as the main pump for…
Design
Cohort
Follow-up
before and after CPB
Authors
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May attenuate thrombin activation in CPB without altering other markers; hypothesis-generating and requires randomized confirmation before practice change.
Does the use of centrifugal pumps compared to roller pumps reduce damage to blood elements and coagulation system activation in patients undergoing open heart surgery?
The use of centrifugal pumps during cardiopulmonary bypass may suppress thrombin synthesis compared to roller pumps, though it does not significantly alter other blood or immune parameters.
Yoshikai et al. (1996) studied this question.
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