Why the study?
Does the Microbumintest tablet method accurately detect microalbuminuria compared to radio-immunoassay in diabetic patients?
Does the Microbumintest tablet method accurately detect microalbuminuria compared to radio-immunoassay in diabetic patients?
Microbumintest tablets provide a highly sensitive and specific, albeit relatively expensive, method for screening microalbuminuria in diabetic patients.
Supports Microbumintest for microalbuminuria screening in diabetes; leaves open prospective validation versus radio-immunoassay.
Microalbuminuria is an important predictor of the development of clinical nephropathy in diabetic patients. In this study we have evaluated the sensitivity and specificity of a rapid semi-quantitative method for the detection of microalbuminuria (Microbumintest tablets) in comparison with radio-immunoassay. When the cut-off point for albumin concentration was set at greater than or equal to 40 mg/l the sensitivity and specificity were 97.2% and 92.2%, respectively. Although the tablets are relatively expensive for screening purposes, we conclude that they represent a reliable and convenient screening method for microalbuminuria in diabetic patients.
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Abdul Salam Al-Kassab (1990) studied this question.
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