March 1, 1999Biophysical JournalOpen Access

Model-Independent Analysis of the Orientation of Fluorescent Probes with Restricted Mobility in Muscle Fibers

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Population

Muscle fibers and other cylindrically ordered systems (e.g., oriented lipid bilayer membranes)

Design

Other

Authors

RDRobert E. DaleGuy's Hospital SHSeth C. HopkinsOtsuka (United States)UHU.A. an der HeideUniversity of Pennsylvania

Discussion

Member takes

Implication

Enables refined probe orientation analysis in muscle samples; extends biophysical methods but leaves clinical translation open.

Structured PICO

Population

Muscle fibers and other cylindrically ordered systems (e.g., oriented lipid bilayer membranes)

Intervention

Model-independent analysis method using steady-state polarized fluorescence

Outcome

Average second-rank and fourth-rank order parameters (<P2> and <P4>) of the angular distribution of c relative to F, and <P2a> and <P2e>

A new model-independent analytical method allows for the characterization of fluorescent probe wobble and its removal from static orientational distribution data in ordered biological samples like muscle fibers.

Cite This Study

Dale et al. (1999) studied this question.

synapsesocial.com/papers/6a711d4ea528af2d65c3ea5c https://doi.org/10.1016/s0006-3495(99)77320-0

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Model-Independent Analysis of the Orientation of Fluorescent Probes with Restricted Mobility in Muscle Fibers

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Model-Independent Analysis of the Orientation of Fluorescent Probes with Restricted Mobility in Muscle Fibers

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider